SALT WASTING NEPHROPATHY(SWN) – IMPORTANT QUESTIONS

J WOON, R NARENTHIRAN, M WEERASINGHE, R ISLAM, MCCLELLAND P.

Goulburn Valley Health, Shepparton, VIC

Aim; One of the most important aspects of recognizing SWN is to be aware of the condition. We would like to raise awareness of the condition and also make it easier to identify by non-specialists.

Background; We designed a questionnaire to identify patients with SWN from features such as symptoms of salt depletion, to blood pressure, diet, bowel habits and other systemic symptoms. Questions were also posed to rule out alternative causes of salt wasting, such as enteropathy, diabetes mellitus and diuretic therapy.

Methods; Volunteers from patients routinely attending their general practitioner were requested to fill in the questionnaire.

Results; From 295 responses, 74 (25%) were excluded as being alternative salt wasters or had spoiled questionnaires (6). 101 responses were designated as having SWN and these were compared to the remaining 120 which acted as the control group. The responses in these two groups were assessed by multivariate analysis. Significant (0.05 or less) differences were found in symptoms of thirst (Odds ratio, 95% C.I.; 45.3, 12.4-165.7), salt craving (19.2, 4.9-74.8), cramps (34.4, 4.7-252.9), hypotension (8.4, 2.1-33.3), postural dizziness (21.1, 2.7-164.5), headaches (8.8, 2.0-38.5), hypertension (0.16, 0.04-0.64), nocturnal enuresis (4.8, 1.05-22.2) and constipation (3.5, 0.98-12.8).

Conclusion; We believe with more data and question refinement, we can provide easy, objective diagnosis of SWN.

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The ASM is hosted by Australian and New Zealand Society of Nephrology.

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