PREVALENCE AND SEROCONVERSION OF HEPATITIS C VIRUS AMONG HAEMODIALYSIS PATIENTS IN PEMALANG, INDONESIA

AZIZ MN1,PARTININGRUM DL1,ARWANTO A1,CHASANI S1, LESTARININGSIH L1

1Division of Nephrology and Hypertension, Internal Medicine Department, Medical Faculty of Diponegoro University/Dr. Kariadi Hospital Semarang

Aim: This study to evaluate the prevalence and seroconvesion of hepatitis C virus (HCV) among hemodialysis patient in Pemalang, Indonesia

Backgraound: Hepatitis C virus (HCV) remains a problem within hemodialysis units.  Many studies have shown that incidence of HCV transmission continue to occur in haemodialysis centers and prevalence and seroconversion greatly vary among haemodialysis facilities. More recent studies in some haemodialysis facilities have shown decline in seroconversion,where as the transmission of the disease continues to persist within several dialysis units.

Method: The study was prospective observational study done in 36 patients on maintenance haemodyalisis serological test for antibodies using Elisa was done. This serological test was repested to see any seroconversion after 3 months.

Result: The mean age of haemodialysis patients was year 47 years.  Among the patients 44.6% were female and 55.4% were male the main duration of haemodialysis was 24 month. The prevalence of HCV was 44.4% (16 of 36). The seroconverssion of HCV after 3 month was  30.5% (11 of 36).

Conclusions: The prevalence of HCV was higher than the national prevalence of HCV in haemodialysis patients by 1% taken from Indonesian Renal Registry (IRR) 2013 Seroconversion of HCV after 3 months was 30,5%(11 of 36).  Early detection of HCV is important in patients with CKD undergoing hemodialysis because of the high prevalence of infection and the requirement.

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