S HIDAYAT1, D PARTININGRUM2, A NURANI2, A ARWANTO2, S CHASANI2, L LESTARININGSIH2
1Indonesian Society Of Nephrology, Semarang , Indonesia, 2Division of Nephrology and Hypertension, Department of Internal Medicine, Diponegoro University/Dr Kariadi Hospital, Semarang, Indonesia
Aim: This study aimed to obtain histopathological characteristics of glomerulonephritis patients who underwent kidney biopsy.
Background: Diagnosis of glomerular diseases remains a challenge as its clinical manifestations may vary but often similar. kidney biopsy is a gold standard for definitive diagnosis to guide nephrologists to estimate accurate prognostication and to formulate treatment.
Methods: This is a descriptive study involving data of 67 glomerulonephritis patients underwent kidney biopsy in dr. kariadi hospital in semarang during the period of september 2016 until april 2018. secondary data were collected from medical records.
Results: Total of 67 patients with presumed glomerular diseases were underwent kidney biopsy with 43 were females (64%) and 24 were males (36%). the median of age was 29 (16-58) year. clinical diagnosis of patients were nephrotic syndrome (54%) and nephritic syndrome (46%). the histopathological results of kidney biopsies were lupus nephritis (49.3%), iga nephropathy (25.4%), post infectious glomerulonephritis (9%), focal segmental glomerulosclerosis (7.5%), minimal change disease (3%), membranoproliferative glomerulonephritis (1.5%), membranous nephropathy (1.5%), chronic pylonephritis (1.5%), tuberculosis (1.5%)
Conclusions: The most common clinical diagnosis of the glomerulonephritis patients is nephrotic syndrome. the majority of biopsy proven glomerulonephritis are immune-mediated glomerular diseases with predominantly histopathological features of lupus nephritis and ig a nephropathy.
Selamet Hidayat completed Medical Doctor Degree from Diponegoro University, Indonesia. He received his Master of Public Health Degree from the Royal Tropical Institute, Amsterdam, The Netherlands. He is currently completing Residency program in Internal Medicine at Diponegoro University/Dr Kariadi Hospital in Semarang, Central Java, Indonesia. He is a member of Indonesian Society of Nephrology (InaSN). In his free time he enjoys reading novels and playing with his children.