E HOURN1, A PARNHAM1, A RAHMAN1
1Gold Coast University Hospital, , Australia
Loin pain haematuria syndrome (LPHS) is a chronic pain syndrome diagnosed by exclusion; patients are often opioid-dependent and have failed multiple surgical and radiological treatments. This series details the novel use of catheter-based endovascular renal denervation for treatment of LPHS in four patients. The procedure was performed unilaterally or bilaterally and had varying success in a diverse patient population inclusive of patients with underlying anatomical abnormalities of medullary sponge kidney, congenital single kidney and autosomal dominant polycystic kidney disease. Two of the four patients have had complete resolution of pain and an additional patient gained significant pain reduction. We hypothesise that repeated procedures may be successful based on one patient with resolution of pain after endovascular denervation that recurred post auto-transplant. The pre-existing comprehensive safety data and this proof of concept case series bolsters the existing theoretical benefit of this procedure for this indication and make it an attractive avenue for further studies.
Ellen Hourn is a nephrology advanced trainee at the Gold Coast University Hospital.