THE IMPACT OF DIALYZER MEMBRANE ON END-STAGE RENAL DISEASE PATIENTS’ QUALITY OF LIFE: A MULTICENTER STUDY IN JAKARTA, INDONESIA

L AZIZA1, SUHARDJONO1, A LYDIA1, M MARBUN1, W SIANIPAR2, L LUTHARIANA3
1Department Of Internal Medicine, Faculty Of Medicine, Universitas Indonesia – Cipto Mangunkusumo Hospital, Jakarta, Indonesia, 2Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia, 3Department of Internal Medicine, Koja District Hospital, Jakarta, Indonesia

Aim: We conducted a multicenter study to determine the association between dialyzer membrane and end-stage renal disease patients’ quality of life.
Background: According to the 8th Report of Indonesian Renal Registry in 2015, there was an annual increase in the prevalence of Indonesia’s hemodialysis patients. However, quality of life in Indonesia’s hemodialysis patients remain unknown. Little is known on the impact of dialyzer membrane on patients’ quality of life.
Methods: We conducted a multicenter study at Cipto Mangunkusumo Hospital, Koja District Hospital, and Cengkareng District Hospital with a total of 389 patients. Cipto Mangunkusumo Hospital represented single-use dialyzer group. Koja and Cengkareng District Hospital represented reusable dialyzer group. Face-to-face interviews were conducted with Kidney Disease Quality of Life-Short Form 36 (KDQOLSF-36) questionnaires.
Results: Of all patients, 57.6% were male. The mean age of patients in this study was 49.3 years (SD 11.5). Single-use dialyzer group’s scores were significantly higher than reusable dialyzer group’s scores in the following main dimensions: kidney disease component summary or KDCS (74.2 vs 66.3; p <0.001), physical component summary or PCS (70.6 vs 55.2; p <0.001), mental component summary or MCS (76.1 vs 70.7; p = 0.023), and overall health rating (73.4 vs 64.9; p <0.001). In the linear regression model, reusable dialyzer was still a strong predictor in KDCS (coefficient β = -8.9; p <0.001), PCS (coefficient β = -17.8; p <0.001), and MCS (coefficient β = -7.6; p = 0.028).
Conclusions: There was a significant association between dialyzer membrane and hemodialysis patients’ quality of life in Jakarta.


Biography:
Dr. Lucky Aziza was born in Jakarta on October 17th, 1959. She earned her medical doctor degree from Faculty of Medicine, Universitas Indonesia in 1983. In 1996, she graduated from internal medicine residency at Universitas Indonesia and had practiced as an internist since then. She earned the degree of nephrology consultant in 2003 and obtained doctoral degree in 2011. She is now working as a staff of Department of Internal Medicine, Cipto Mangunkusumo National Teaching Hospital. She is also active as a lecturer at Universitas Indonesia and was awarded “Excellent Teaching Staff Award from The Dean” from 2014 to 2017

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