EVALUATING THE ASSOCIATION BETWEEN QUALITY OF LIFE AND DIALYSIS TREATMENT PARAMETERS IN PATIENTS ON HEMODIALYSIS

M H DANG1,2, J HENDERSON1, X STEVEN1, R  RAJ2, K WONG1

1Peninsula Health, Frankston, Australia , 2Launceston General Hospital, Launceston, Australia

Aim: To evaluate the association between quality of life and dialysis treatment hours in patients on in-centre hemodialysis.
Background: Quality of life (QOL) in patients on in-centre haemodialysis remains poor and difficult to improve. Dialysis parameters such as treatment time could affect QOL, as could ultrafiltration rates or dialysis efficiency. Modifications of the haemodialysis prescription are potentially attractive interventions to improve QOL in this population.
Methods: We performed a cross-sectional study in a convenience sample of adult, in-centre haemodialysis patients between June – August 2019 across two satellite haemodialysis units in outer metropolitan Melbourne. Demographic variables and treatment parameters (time, ultrafiltration rate, urea reduction) were collected. Relationships were investigated  between these variables and QOL, measured using the WHOQOL-BREF questionnaire, which assesses 4 domains (physical, psychological, relationships and environmental).
Results: 48 participants were recruited (mean age 69.3 ±12; 65% male, mean dialysis vintage 4.73 years). Participants were classified into 3 groups based on treatment hours: 15 hours (n=13), 13.5 hours (n=26) or <13.5 hours (n=9) per week. There were no statistically significant differences across 4 domains of quality of life between the 3 groups, (p-values 0.49, 0.59, 0.27 and 0.77 for QOL domains respectively). Other modifiable treatment parameters (urea reduction ratio, ultrafiltration rate) also had no significant effects on QOL domains. Among other variables, antidepressant use was associated with lower psychological domain scores. Dialysis vintage, comorbidities, hemoglobin or albumin levels did not correlate with QOL domain scores.
Conclusions: Routine dialysis treatment parameters were not correlated with QOL domains in this study, highlighting the complexities of improving overall QOL in patients on hemodialysis.


Biography:
Dr Minh Huan Dang is a second year Nephrology Advanced Trainee at Launceston General Hospital. His main research interest is in quality of life in patients on dialysis.

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