G MAULANA1, R PRASANTO2, DR IRI KUSWADI3
1Renal and Hypertension Division, Internal Medicine Department, Sardjito Hospital, Yogyakarta, Indonesia, 2Renal and Hypertension Division, Internal Medicine Department, Sardjito Hospital, Yogyakarta, Indonesia, 3Renal and Hypertension Division, Internal Medicine Department, Sardjito Hospital, Yogyakarta, Indonesia
Background: Hyperaldosteronism, also aldosteronism is a medical condition wherein too much aldosterone is produced by the adrenal glands, which can lead to lowered levels of potassium in the blood (hypokalemia) and increased hydrogen ion excretion (alkalosis). Most common cause of mineralocorticoid excess is primary hyperaldosteronism reflecting excess production of aldosterone by adrenal zone glomerulosa. This report is about adult female with hyperaldosteronism which already diagnosed 2 years with hypertension only.
Case Report: A 66 years old woman with complaints of chronic headaches. It has been known to suffer from hypertension since the last 2 year. From the initial physical examination obtained the neck muscle spasms and hypertension (190/120 mmHg). Laboratory findings obtained hypernatremia, hypokalemia, metabolic alkalosis, increased levels of plasma aldosterone, decreased levels of plasma renin activity, sodium excretion fraction decreased, and increased TTKG. Diagnosed with Hyperaldosteronism. Medical treatment: Telmisartan 80 mg once daily, Spironolactone 100 mg once daily, Bisoprolol 2.5 mg once daily, Amlodipine 10mg once daily. The patient’s condition improved and laboratory profiles improved in the last 5 months after starting therapy.
Conclusion:. Hyperaldosteronisme is a condition that is quite common but often under diagnosed. Further investigation is needed to evaluate cause of hypertension.
Gusti Hariyadi Maulana is internist from Banjarbaru, South Kalimantan who currently studying Nephrology in Yogyakarta. He got Young Investigator Award in PIT PERNERI 2017 (2017 Annual Indonesia Nephrology Congress).