Experimental Tubolointerstitial Disease

M LEE1,2, P MOUNT1, M KATERELOS1, K GLEICH1, D POWER1,2 1Austin Health, Heidelberg, Australia, 2Department of Medicine, The University of Melbourne, Heidelberg, Australia Aim: To determine the roles of fatty acid oxidation (FAO) and glycolysis in renal fibrosis. Background: Changes...
C HUANG1, H YI1, Y SHI1, Q CAO1, X-M CHEN1, C POLLOCK1 1University of Sydney, St Leonards, Australia Aim: To identify the role of KCa3.1 in mitochondrial quality control in diabetic nephropathy. Background: Mitochondrial dysfunction is involved in the pathogenesis...
J JHA1, R TOUYZ2, C KENNEDY3, M COOPER1, K JANDELEIT-DAHM1 1Department Of Diabetes, Melbourne, Australia, 2Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom, 3Department of Medicine, Ottawa Hospital Research Institute, Ottawa, Canada Background: Renal reactive oxygen...
KG LEONG1,2, E OZOLS1,2, J KANELLIS1,2, J LILES3,D NIKOLIC-PATERSON1,2, F MA1,2 1Department of Nephrology, Monash Medical Centre, Clayton, Australia, 2Centre for Inflammatory Disease, Monash University, Clayton, Australia, 3Gilead Sciences, Foster City, USA Aims: Determine whether therapeutic inhibition of cyclophilin (Cyp)...
J WANG1, Q CAO1, Y WANG1, D HARRIS1, G ROBERTSON2, D BURG2, M HALASZ2, V LEE1 1Westmead Institute Of Medical Research, Westmead, Australia, 2Cellmid Limited, Sydney, Australia Aim: To determine the efficacy of anti-Midkine (MK) antibodies in ameliorating kidney damage and...
Y SHI1,  C HUANG1, X CHEN1, C POLLOCK1 1Kolling Institute, Royal North Shore Hospital, St Leonards, Australia Aim: To define the role of receptor-interacting protein kinase 3 (RIPK3) in alleviating renal fibrogenesis. Background: Current therapies for renal fibrosis are largely...
S REDZEPAGIC1, C HUANG1, C POLLOCK1, U PANCHAPAKESAN1 1Renal Research Group, Kolling Institute, Royal North Shore Hospital, University of Sydney, Sydney, Australia Aim: To assess if primary cilial Protein#1 is regulated by transforming growth factor beta (TGFB1) and evaluate if...
P SAGAR1,2, J ZHANG1,2, C MANNIX1,2, AT WONG1,2, G RANGAN1,2 1Centre for Transplant and Renal Research, Westmead Institute of Medical Research, University of Sydney, Sydney, Australia, 2Department of Renal Medicine, Westmead Hospital, Western Sydney Local Health District, Sydney, Australia Aim:...
L SUCCAR1,  J WONG1, K TAYLOR1, A AU1, J ERLICH1, E ZOLTAN1 1University of New South Wales, Department of Nephrology, Prince of Wales Clinical School., Randwick, Sydney, Australia Aim: To investigate biomarker profiles when ischaemic sAKI is superimposed on sCKD....
T MULLINS1,2, W SHENG TAN1, L GALLO1,2 1School Of Biomedical Sciences, The University of Queensland, St Lucia, Australia, 2Mater Research Institute-UQ, Translational Research Institute, Woollongabba, Australia Aim: To validate a non-invasive transcutaneous method for assessing glomerular filtration rate (GFR) in obese...
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