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Professor of Medicine at Flinders University and Consultant Nephrologist at Flinders Medical Centre.Jonathan Gleadle is Professor of Medicine at Flinders University and Consultant Nephrologist at Flinders Medical Centre. He leads the Clinical Disciplines in the College of Medicine and Public Health at Flinders. He undertook a DPhil at Oxford entitled “The mechanism of oxygen sensing by mammalian cells”. He was then University Lecturer in Nephrology and General Medicine at the University of Oxford (1997-2007). Research during this time contributed to the body of work which was recognised by the award of the 2019 Nobel Prize in Medicine to Peter Ratcliffe for how cells sense oxygen, with contributions to 23 co-authored publications (including 5 as first author and 3 as senior author) including characterising and naming the prolyl hydroxylase enzymes (PHD 1-3) which sense oxygen. He has generated over 95 highly cited publications in the fields of oxygen sensing, microRNAs and clinical nephrology. Current research focusses on the mechanism underlying compensatory renal hypertrophy, the translation and clinical relevance of urine diagnostics in cancer and the molecular and cellular responses to oxygen. He has lead the creation of multiple medical student and trainee physician textbooks, most recently “How to Pass the FRACP Written Examination”. |